LiverXreceptor相关论文
Effect of Quercetin on Atherosclerosis Based on Expressions of ABCA1, LXR-α and PCSK9 in ApoE-/-Mice
Objective:To investigate the effect of quercetin on ATP binding cassette transporter A1 (ABCA1),liver X receptor (LXR),a......
Effects of marine collagen peptides on glucose and lipid metabolism and markers of metabolic nuclear
Objective:This study was attempted to determine the effects of marine collagen peptides(MCPs) on glucose and lipid metab......
Comparison of Tolerogenic Dendritic Cells Induced by Liver X Receptor Agonist from Bone Marrow-deriv
Background: Mouse dendritic cells (DCs) possessed the tolerogenic potentiality after induced by liver X receptor (LXR) a......
Biliary cholesterol may contribute to the formation of cholesterol gallstones, regulation of these levels could be a use......
We have previously reported that endogenous (oxysterols) as well as synthetic (GW3965, TO0901317) ligands of Liver X Rec......
Roles of nuclear receptors LXRs and ERs in the neuroprotection of dopaminergic neurons in the midbra
Objective To explore the roles of liver x receptors (LXRs) and estrogen receptors (ERs) in the activation of microglia a......
Liver X receptors(LXRs)are ligand activated transcription factors that belong to the nuclear receptor superfamily.LXRs p......
Atherosclerosis is the most common cause of cardiovascular diseases, such as myocardial infarction and stroke.The aim of......
Ezetimibe Protects Vascular Smooth Muscle Cells from Cholesterol Accumulation via SREBP-1/Caveolin-1
Aim To investigate the effects of ezetimibe on intracellular cholesterol level, and the mechanisms underlying the protec......
肝脏的低密度脂蛋白受体(LDLR)是清除血浆低密度脂蛋白(LDL)的主要途径,并且是一个非常重要的心血管系统疾病的治疗靶点.LDLR的表......
目的 观察肝X受体激动剂T0901317对脂多糖诱导的THP-1巨噬细胞炎症因子释放的影响,并探讨其机制.方法 160 nmol/L佛波酯孵育THP-1......
近年来,随着脂肪肝病患者的增多,对低密度脂蛋白受体家族的研究也逐步深入,其中极低密度脂蛋白受体( VLDLR)已逐渐成为医学、生理学与分......
肝X受体是孤核受体超家族成员之一,其天然配体为氧化固醇,越来越多的证据表明,肝X受体可能对心脏具有直接的有益作用。心力衰竭是心血......